Compile Data Set for Download or QSAR
maximum 50k data
Found 7 Enz. Inhib. hit(s) with Target = 'Gamma-butyrobetaine dioxygenase' and Ligand = 'BDBM50028968'
TargetGamma-butyrobetaine dioxygenase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50028968(CHEMBL3335712)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of human BBOX pre-incubated for 25 mins using TBS-protected fluorescein probe and Fe (II) (Fe(NH4)2(SO4)2 salt by fluoride release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-butyrobetaine dioxygenase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50028968(CHEMBL3335712)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of human BBOX pre-incubated for 20 mins using TBS-protected fluorescein probe and Fe (II) (Fe(NH4)2(SO4)2 salt by fluoride release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-butyrobetaine dioxygenase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50028968(CHEMBL3335712)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of human BBOX pre-incubated for 15 mins using TBS-protected fluorescein probe and Fe (II) (Fe(NH4)2(SO4)2 salt by fluoride release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-butyrobetaine dioxygenase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50028968(CHEMBL3335712)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human BBOX pre-incubated for 10 mins using TBS-protected fluorescein probe and Fe (II) (Fe(NH4)2(SO4)2 salt by fluoride release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-butyrobetaine dioxygenase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50028968(CHEMBL3335712)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of human BBOX pre-incubated for 1 min using TBS-protected fluorescein probe and Fe (II) (Fe(NH4)2(SO4)2 salt by fluoride release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-butyrobetaine dioxygenase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50028968(CHEMBL3335712)
Affinity DataKd:  7.50E+3nMAssay Description:Binding affinity to human BBOX in presence of Fe(II) by tryptophan fluorescence quenching binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-butyrobetaine dioxygenase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50028968(CHEMBL3335712)
Affinity DataKd:  9.40E+3nMAssay Description:Binding affinity to human BBOX by tryptophan fluorescence quenching binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed