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Found 4 Enz. Inhib. hit(s) with Target = 'Genome polyprotein' and Ligand = 'BDBM11243'
TargetGenome polyprotein(Norovirus Hu/GII.P4_GII.4/Minerva)
Emory University

US Patent
LigandPNGBDBM11243(AG7088 | CHEMBL20210 | US11859014, Compound rupint...)
Affinity DataKi:  8.20E+3nMAssay Description:The ability of these compounds to inhibit the NoV, specifically Minerva virus protease catalytic Cys139 covalently (IC50 and Ki) was determined with ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Human rhinovirus B)
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM11243(AG7088 | CHEMBL20210 | US11859014, Compound rupint...)
Affinity DataIC50:  23nMAssay Description:Reversible inhibitory activity of the compound was determined against ProteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Norovirus Hu/GII.P4_GII.4/Minerva)
Emory University

US Patent
LigandPNGBDBM11243(AG7088 | CHEMBL20210 | US11859014, Compound rupint...)
Affinity DataIC50:  2.36E+4nMAssay Description:The ability of these compounds to inhibit the NoV, specifically Minerva virus protease catalytic Cys139 covalently (IC50 and Ki) was determined with ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Human rhinovirus B)
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM11243(AG7088 | CHEMBL20210 | US11859014, Compound rupint...)
Affinity DataEC50:  5nMAssay Description:Increased percentage of formazan production in drug treated virus infected cells to equal 50% control drug free uninfected cells on serotype 14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed