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Found 4 Enz. Inhib. hit(s) with Target = 'Genome polyprotein' and Ligand = 'BDBM204721'
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM204721(US9243002, 58 | US9243002, 59)
Affinity DataIC50:  1.52nMAssay Description:To initiate an assay, replicon cells were plated in the presence of a dilution series of test compound in the absence of G418. Typically, the assays ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM204721(US9243002, 58 | US9243002, 59)
Affinity DataIC50:  1.71nMAssay Description:To initiate an assay, replicon cells were plated in the presence of a dilution series of test compound in the absence of G418. Typically, the assays ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM204721(US9243002, 58 | US9243002, 59)
Affinity DataIC50:  2.90nMAssay Description:To initiate an assay, replicon cells were plated in the presence of a dilution series of test compound in the absence of G418. Typically, the assays ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM204721(US9243002, 58 | US9243002, 59)
Affinity DataIC50:  5.45nMAssay Description:To initiate an assay, replicon cells were plated in the presence of a dilution series of test compound in the absence of G418. Typically, the assays ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent