Found 10 Enz. Inhib. hit(s) with Target = 'Genome polyprotein' and Ligand = 'BDBM50142916' 
Affinity DataKi: 0.0890nMAssay Description:Inhibition of HCV genotype-1a NS3 proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.120nMAssay Description:Analysis of the inhibition activation of flNS3 by the inhibitors was performed with the standard assay, allowing the inhibitor to preincubate with NS...More data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Inhibition of HCV genotype 1a NS3/4A protease using Ac-DED(Edans)EEAbu-psi[COO]ASK(Dabcyl)-NH2 as substrate by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Inhibition of HCV 1a NS3 proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Inhibition of HCV genotype-3a full length NS3 protease preincubated for 10 mins followed by Ac-DED(Edans)EEAbuj-[COO]ASK(Dabcyl)-NH2 addition in pres...More data for this Ligand-Target Pair
Affinity DataKi: 24nMAssay Description:Inhibition of full-length HCV NS3 protease R155K mutantMore data for this Ligand-Target Pair
Affinity DataKi: 120nMAssay Description:Inhibition of full-length HCV NS3 protease A156T mutantMore data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Uppsala University
Curated by ChEMBL
Uppsala University
Curated by ChEMBL
Affinity DataKi: 200nMAssay Description:Inhibition of full-length HCV NS3 protease D168V mutantMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Inhibition of full length Hepatitis C virus genotype 1b Con1 NS3/4A by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibitory concentration against hepatitis C virus NS3 proteaseMore data for this Ligand-Target Pair
