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Found 4 Enz. Inhib. hit(s) with Target = 'Glucagon receptor' and Ligand = 'BDBM50171817'
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50171817(3-(4-((1-(4-tert-butylcyclohexyl)-3-(4-(trifluorom...)
Affinity DataIC50:  21nMAssay Description:Antagonist activity against human glucagon receptor expressed in CHO cell membranes using [125I]glucagonMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Rattus norvegicus)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50171817(3-(4-((1-(4-tert-butylcyclohexyl)-3-(4-(trifluorom...)
Affinity DataIC50:  23nMAssay Description:Binding affinity to GlucR in rat liver membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50171817(3-(4-((1-(4-tert-butylcyclohexyl)-3-(4-(trifluorom...)
Affinity DataIC50:  23nMAssay Description:Binding affinity to human cloned GluR expressed in BHK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50171817(3-(4-((1-(4-tert-butylcyclohexyl)-3-(4-(trifluorom...)
Affinity DataIC50:  144nMAssay Description:Inhibitory concentration against glucagon-induced cAMP accumulation in human glucagon receptor transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed