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Found 7 Enz. Inhib. hit(s) with Target = 'Glucagon receptor' and Ligand = 'BDBM50360601'
TargetGlucagon receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360601(CHEMBL1933349 | MK-0893)
Affinity DataKi:  70nMAssay Description:Displacement of [125I]Glucagon-Cex from human GCGRMore data for this Ligand-Target Pair
TargetGlucagon receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360601(CHEMBL1933349 | MK-0893)
Affinity DataIC50:  6.60nMAssay Description:Displacement of [125I]glucagon from human GCGR expressed in CHO cells after 3 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
TargetGlucagon receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360601(CHEMBL1933349 | MK-0893)
Affinity DataIC50:  16nMAssay Description:Antagonist activity at human GCGR expressed in CHO cells assessed as inhibition of glucagon-induced cAMP accumulation preincubated for 30 mins prior ...More data for this Ligand-Target Pair
TargetGlucagon receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360601(CHEMBL1933349 | MK-0893)
Affinity DataIC50:  20nMAssay Description:Displacement of [125I]-glucagon from wild type human glucagon receptor expressed in CHOK1 cells after 3 hrs by micro beta scintillation counting anal...More data for this Ligand-Target Pair
TargetGlucagon receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360601(CHEMBL1933349 | MK-0893)
Affinity DataIC50:  80nMAssay Description:Antagonist activity at human glucagon receptor expressed in HEK293T cells assessed as inhibition of glucagon-induced cAMP accumulation after 30 mins ...More data for this Ligand-Target Pair
TargetGlucagon receptor(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50360601(CHEMBL1933349 | MK-0893)
Affinity DataIC50:  122nMAssay Description:Antagonist activity at mouse GCGR expressed in CHO cells assessed as inhibition of glucagon-induced cAMP accumulation preincubated for 30 mins prior ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50360601(CHEMBL1933349 | MK-0893)
Affinity DataIC50:  727nMAssay Description:Antagonist activity at rat GCGR expressed in CHO cells assessed as inhibition of glucagon-induced cAMP accumulation preincubated for 30 mins prior to...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed