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Found 7 Enz. Inhib. hit(s) with Target = 'Glutamate carboxypeptidase 2' and Ligand = 'BDBM17755'
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM17755(2-(3-sulfanylpropyl)pentanedioic acid | 2-MPPA | C...)
Affinity DataIC50:  90nMAssay Description:Inhibition of N-acetyl-L-aspartyl-[3H]-L-glutamate binding to glutamate carboxypeptidase II (GCP II)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM17755(2-(3-sulfanylpropyl)pentanedioic acid | 2-MPPA | C...)
Affinity DataIC50:  90nMAssay Description:Inhibition of Glutamate carboxypeptidase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM17755(2-(3-sulfanylpropyl)pentanedioic acid | 2-MPPA | C...)
Affinity DataIC50:  90nMAssay Description:Inhibition of GCP-2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM17755(2-(3-sulfanylpropyl)pentanedioic acid | 2-MPPA | C...)
Affinity DataIC50:  90nMAssay Description:Inhibition of human recombinant GCP2 using N-acetyl-L-aspartyl-[3H]-L-glutamate as substrate by microplate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM17755(2-(3-sulfanylpropyl)pentanedioic acid | 2-MPPA | C...)
Affinity DataIC50:  90nMAssay Description:Inhibition of GCP2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM17755(2-(3-sulfanylpropyl)pentanedioic acid | 2-MPPA | C...)
Affinity DataIC50:  90nMAssay Description:Inhibition of GCP2 by top scintillation counter in presence of 30 nM NAA[3]GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM17755(2-(3-sulfanylpropyl)pentanedioic acid | 2-MPPA | C...)
Affinity DataEC50:  13nMAssay Description:Concentration of the compound required for the neuroprotective effect determined by inhibition of GCP IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed