Found 5 Enz. Inhib. hit(s) with Target = 'Glutamate receptor ionotropic, NMDA 1/2B' and Ligand = 'BDBM50143890' TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
Hamamatsu University School Of Medicine
Curated by ChEMBL
Hamamatsu University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Displacement of [3H]-(E)-N1-(2-methoxybenzyl)cinnamamidine from human NR1a/NR2b receptor expressed in mouse Ltk cellsMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
Hamamatsu University School Of Medicine
Curated by ChEMBL
Hamamatsu University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Compound was evaluated for in vitro inhibition of [3H][(E)-N-(2-methoxybenzyl)cinnamamidine binding to human NR1a/NR2B receptors expressed in LtK-cel...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
Hamamatsu University School Of Medicine
Curated by ChEMBL
Hamamatsu University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 8.20nMAssay Description:Antagonist activity at NR1/NR2B receptor assessed as inhibition of Glu/Gly induced Ca2+ influxMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
Hamamatsu University School Of Medicine
Curated by ChEMBL
Hamamatsu University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 8.20nMAssay Description:In vitro inhibition of Glu/Gly stimulated [Ca2+] influx in LtK-cells expressing the hNR1a/NR2B receptorMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
Hamamatsu University School Of Medicine
Curated by ChEMBL
Hamamatsu University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 209nMAssay Description:Antagonist activity against NR1a/NR2B receptor transfected in human HEK293 cells assessed as inhibition of NMDA-induced Ca2+ influxMore data for this Ligand-Target Pair
