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Found 2 Enz. Inhib. hit(s) with Target = 'Glutamate receptor ionotropic, NMDA 2B' and Ligand = 'BDBM409482'
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM409482(1-(3-Fluoroazetidin-1-yl)-2-[6-(4-fluoro-3-methyl-...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]-1-(azetidin-1-yl)-2-(6-(4-fluoro-3-methylphenyl)-1H-pyrrolo[3,2-b]pyridin-1-yl)ethanone from rat adult cortex GluN2B receptor me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409482(1-(3-Fluoroazetidin-1-yl)-2-[6-(4-fluoro-3-methyl-...)
Affinity DataIC50:  50.1nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent