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Found 2 Enz. Inhib. hit(s) with Target = 'Glutamate receptor ionotropic, NMDA 2B' and Ligand = 'BDBM50269759'
TargetGlutamate receptor ionotropic, NMDA 2B(Mus musculus)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50269759(CHEMBL4093543)
Affinity DataIC50:  25nMAssay Description:Antagonist activity at mouse NR2B expressed in Hek293 cells co-expressing mouse NR1 assessed as inhibition of glutamic acid/glycine-induced intracell...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50269759(CHEMBL4093543)
Affinity DataIC50:  40nMAssay Description:Displacement of [3H]-ifenprodil from NR2B in Wistar rat brain membrane after 120 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed