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Found 3 Enz. Inhib. hit(s) with Target = 'Glycogen synthase kinase-3 beta' and Ligand = 'BDBM50134187'
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Angelini Pharma

Curated by ChEMBL
LigandPNGBDBM50134187(CHEMBL3735506 | US11472795, Example C | US9611249,...)
Affinity DataIC50:  18nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged GSK3beta (1 to 420 end residues) expressed in baculovirus expression system using u...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Angelini Pharma

Curated by ChEMBL
LigandPNGBDBM50134187(CHEMBL3735506 | US11472795, Example C | US9611249,...)
Affinity DataIC50:  20nMAssay Description:Activity on human GSK-3β was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screen...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Angelini Pharma

Curated by ChEMBL
LigandPNGBDBM50134187(CHEMBL3735506 | US11472795, Example C | US9611249,...)
Affinity DataIC50:  21.6nMAssay Description:The activity on human GSK-3β of the compounds of the invention listed in the following Table 1 and of the comparison compound C was assessed at ...More data for this Ligand-Target Pair