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Found 7 Enz. Inhib. hit(s) with Target = 'Heat shock protein HSP 90-alpha/90-beta' and Ligand = 'BDBM50005781'
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50005781(ALVESPIMYCIN | CHEBI:65324)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of Hsp90 in human MDA-MB-231 cells assessed as her2 degradationMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50005781(ALVESPIMYCIN | CHEBI:65324)
Affinity DataIC50:  18nMAssay Description:Inhibition of Hsp90 in human MDA-MB-231 cells assessed as Akt degradationMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50005781(ALVESPIMYCIN | CHEBI:65324)
Affinity DataIC50:  24nMAssay Description:Inhibition of Hsp90 in human A2058 cells assessed as Akt degradationMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50005781(ALVESPIMYCIN | CHEBI:65324)
Affinity DataIC50:  24nMAssay Description:Inhibition of Hsp90 in human SKBR3 cellsMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50005781(ALVESPIMYCIN | CHEBI:65324)
Affinity DataIC50:  24nMAssay Description:Inhibition of Hsp90 in human SKBR3 cellsMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50005781(ALVESPIMYCIN | CHEBI:65324)
Affinity DataIC50:  100nMAssay Description:Inhibition of Hsp90 in human H1299 assessed as degradation of Hsp90 client protein AktMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50005781(ALVESPIMYCIN | CHEBI:65324)
Affinity DataEC50:  7.90nMAssay Description:Inhibition of Hsp90 in human A2058 cellsMore data for this Ligand-Target Pair