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Found 5 Enz. Inhib. hit(s) with Target = 'Heat shock protein HSP 90-alpha/90-beta' and Ligand = 'BDBM50479788'
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50479788(CHEMBL486750)
Affinity DataIC50:  7.60nMAssay Description:Inhibition of Hsp90 in human MDA-MB-231 cells assessed as her2 degradationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50479788(CHEMBL486750)
Affinity DataIC50:  19nMAssay Description:Inhibition of Hsp90 in human MDA-MB-231 cells assessed as Akt degradationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50479788(CHEMBL486750)
Affinity DataIC50:  20nMAssay Description:Inhibition of Hsp90 in human H1299 cells after 24 hrs by Akt luminex assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50479788(CHEMBL486750)
Affinity DataIC50:  34nMAssay Description:Inhibition of Hsp90 in human A2058 cells assessed as Akt degradationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50479788(CHEMBL486750)
Affinity DataEC50:  18nMAssay Description:Inhibition of Hsp90 in human A2058 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed