Compile Data Set for Download or QSAR
maximum 50k data
Found 5 Enz. Inhib. hit(s) with Target = 'Heat shock protein HSP 90-alpha/90-beta' and Ligand = 'BDBM50479790'
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50479790(CHEMBL486547)
Affinity DataIC50:  17nMAssay Description:Inhibition of Hsp90 in human MDA-MB-231 cells assessed as her2 degradationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50479790(CHEMBL486547)
Affinity DataIC50:  27nMAssay Description:Inhibition of Hsp90 in human H1299 cells after 24 hrs by Akt luminex assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50479790(CHEMBL486547)
Affinity DataIC50:  42nMAssay Description:Inhibition of Hsp90 in human MDA-MB-231 cells assessed as Akt degradationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50479790(CHEMBL486547)
Affinity DataIC50:  50nMAssay Description:Inhibition of Hsp90 in human A2058 cells assessed as Akt degradationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50479790(CHEMBL486547)
Affinity DataEC50:  41nMAssay Description:Inhibition of Hsp90 in human A2058 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed