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Found 3 Enz. Inhib. hit(s) with Target = 'Heat shock protein HSP 90-alpha' and Ligand = 'BDBM50165286'
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50165286(8-(2,4-Dimethyl-phenylsulfanyl)-9-pent-4-ynyl-9H-p...)
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of human cy3B-GM labeled Hsp90alpha expressed in Escherichia coli BL21(DE3) measured after 24 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50165286(8-(2,4-Dimethyl-phenylsulfanyl)-9-pent-4-ynyl-9H-p...)
Affinity DataIC50: >3.00E+5nMAssay Description:Displacement of Cy3B-GM from recombinant Hsp90alpha (unknown origin) after 24 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Mus musculus)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50165286(8-(2,4-Dimethyl-phenylsulfanyl)-9-pent-4-ynyl-9H-p...)
Affinity DataEC50:  8.60E+3nMAssay Description:Displacement of 5 nM GM-BODIPY from mouse heat shock protein HSP90-alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed