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Found 5 Enz. Inhib. hit(s) with Target = 'Heat shock protein HSP 90-alpha' and Ligand = 'BDBM50347503'
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50347503(RADICICOL)
Affinity DataIC50:  16nMAssay Description:Binding affinity to Hsp90alpha N-terminal ATPase domain by TR-FRET assay based competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50347503(RADICICOL)
Affinity DataIC50:  530nMAssay Description:Inhibition of Hsp90alpha ATPase activity by malachite green ATP-ase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50347503(RADICICOL)
Affinity DataKd:  19nMAssay Description:The compound was tested for binding affinity against yeast Heat shock protein HSP 90More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50347503(RADICICOL)
Affinity DataKd:  4.20nMAssay Description:Binding affinity to recombinant Hsp90 alpha (unknown origin) by surface plasmon resonanceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50347503(RADICICOL)
Affinity DataKd:  2.70nMAssay Description:The compound was tested for binding affinity against isolated N-domain of Heat shock protein HSP 90More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed