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Found 2 Enz. Inhib. hit(s) with Target = 'Hexokinase-4' and Ligand = 'BDBM249127'
TargetHexokinase-4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM249127(US9453038, 4)
Affinity DataEC50:  11.4nMT: 2°CAssay Description:To test the exemplified compounds, the following assay was employed. Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHexokinase-4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM249127(US9453038, 4)
Affinity DataEC50:  21.8nMT: 2°CAssay Description:To test the exemplified compounds, the following assay was employed. Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent