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Found 2 Enz. Inhib. hit(s) with Target = 'High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A' and Ligand = 'BDBM477952'
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences

US Patent
LigandPNGBDBM477952(6-(azetidin-1-yl)-2-oxo-4-(6-azaspiro[2.5]octane-6...)
Affinity DataIC50:  9nMAssay Description:Test substance: Compounds of the invention, prepared by the corresponding examples of the invention1. Experimental materials and instrumentsPDE9A2 En...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences

US Patent
LigandPNGBDBM477952(6-(azetidin-1-yl)-2-oxo-4-(6-azaspiro[2.5]octane-6...)
Affinity DataIC50:  9nMAssay Description:1. Experimental materials and instrumentsPDE9A2 Enzyme (BPS, Cat. No. 60090)384-well plate (Perkin Elmer, Cat. No. 6007279)2. Experimental procedureP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent