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Found 1 Enz. Inhib. hit(s) with Target = 'High affinity nerve growth factor receptor [G595R]' and Ligand = 'BDBM515359'
TargetHigh affinity nerve growth factor receptor [G595R](Homo sapiens (Human))
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM515359((13E,14E,22R,24S)-12-amino-24,35-difluoro- 8-methy...)
Affinity DataIC50:  1.05nMAssay Description:TrkAG595R (Kinase domain) kinase was expressed in Sf9 cells using pIEX-Bac-4, and purified by using affinity chromatography on AKTA Purifier (GE comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent