Found 8 Enz. Inhib. hit(s) with Target = 'Histamine H1 receptor' and Ligand = 'BDBM50017376' TargetHistamine H1 receptor(Homo sapiens (Human))
The Schering Plough Research Institute
Curated by ChEMBL
The Schering Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 40nMAssay Description:Displacement of [3H]pyrilamine from human recombinant histamine H1 receptor expressed in CHO cell by betaplate scintillation countingMore data for this Ligand-Target Pair
TargetHistamine H1 receptor(Homo sapiens (Human))
The Schering Plough Research Institute
Curated by ChEMBL
The Schering Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 58nMAssay Description:Binding affinity towards histamine H1 receptorMore data for this Ligand-Target Pair
TargetHistamine H1 receptor(Homo sapiens (Human))
The Schering Plough Research Institute
Curated by ChEMBL
The Schering Plough Research Institute
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of histamine H1 receptor (unknown origin)More data for this Ligand-Target Pair
TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
Wyeth-Ayerst Research
Curated by ChEMBL
Wyeth-Ayerst Research
Curated by ChEMBL
Affinity DataIC50: 94nMAssay Description:Compound is evaluated for in vitro receptor binding affinity against H1 receptorMore data for this Ligand-Target Pair
TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
Wyeth-Ayerst Research
Curated by ChEMBL
Wyeth-Ayerst Research
Curated by ChEMBL
Affinity DataIC50: 295nMAssay Description:Inhibitory activity of the compound against Tritiated [3H]- mepyramine binding to histamine H1 receptor in guinea pig cerebral cortexMore data for this Ligand-Target Pair
TargetHistamine H1 receptor(Homo sapiens (Human))
The Schering Plough Research Institute
Curated by ChEMBL
The Schering Plough Research Institute
Curated by ChEMBL
Affinity DataIC50: 563nMAssay Description:Antagonism of the human histamine H1 receptorMore data for this Ligand-Target Pair
TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
Wyeth-Ayerst Research
Curated by ChEMBL
Wyeth-Ayerst Research
Curated by ChEMBL
Affinity DataKd: 302nMAssay Description:Inhibition of specific binding of [3H]mepyramine to Histamine 1 receptors in guinea-pigMore data for this Ligand-Target Pair
TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
Wyeth-Ayerst Research
Curated by ChEMBL
Wyeth-Ayerst Research
Curated by ChEMBL
Affinity DataKd: 35nMAssay Description:Dissociation constant was determined against H1 receptor of guinea pig lung membranes using radioligand binding assays.More data for this Ligand-Target Pair
