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Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM197117'
Target
Histamine H3 receptor
(Homo sapiens (Human))
Novartis
US Patent
Ligand
BDBM197117
(US9216182, 1.63)
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Affinity Data
Ki: 0.200nM
Assay Description:
The potency of compounds of the invention as H3 receptor antagonists can be assessed by measuring the blockade of (R)-alpha-methylhistamine-mediated ...
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