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Found 5 Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM50278350'
TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50278350(4-fluoro-1-(4-(3-(piperidin-1-yl)propoxy)benzyl)pi...)
Affinity DataKi:  0.0933nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from recombinant human histamine H3 receptor expressed in HEK293 cells after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50278350(4-fluoro-1-(4-(3-(piperidin-1-yl)propoxy)benzyl)pi...)
Affinity DataKi:  0.0940nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from recombinant human histamine H3 receptor expressed in HEK293 cells after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50278350(4-fluoro-1-(4-(3-(piperidin-1-yl)propoxy)benzyl)pi...)
Affinity DataKi:  0.0940nMAssay Description:Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in HEL293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Eth Zurich (Swiss Federal Institute Of Technology)

Curated by ChEMBL
LigandPNGBDBM50278350(4-fluoro-1-(4-(3-(piperidin-1-yl)propoxy)benzyl)pi...)
Affinity DataKd:  0.340nMAssay Description:Binding affinity to rat brain histamine H3 receptor after 1 hr by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Eth Zurich (Swiss Federal Institute Of Technology)

Curated by ChEMBL
LigandPNGBDBM50278350(4-fluoro-1-(4-(3-(piperidin-1-yl)propoxy)benzyl)pi...)
Affinity DataKd: >3.00E+3nMAssay Description:Binding affinity to rat histamine H3 receptor low affinity site after 1 hr by Schard plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed