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Found 7 Enz. Inhib. hit(s) with Target = 'Histone acetyltransferase p300' and Ligand = 'BDBM50456444'
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50456444(CHEMBL3734823)
Affinity DataKi:  400nMAssay Description:Inhibition of VMA intein chitin binding domain-fused p300 HAT domain (1287 to 1652 residues) (unknown origin) expressed in Escherichia coli BL21(RIL)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50456444(CHEMBL3734823)
Affinity DataIC50:  9.80nMAssay Description:Inhibition of P300 BHC domain (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50456444(CHEMBL3734823)
Affinity DataIC50:  320nMAssay Description:Inhibition of human recombinant Histone acetyltransferase p300 catalytic domain (1284-1672 residues) using [3H]Acetyl-CoA and histone H3 substrate at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50456444(CHEMBL3734823)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of P300 (unknown origin) (1287 to 1652 residues) expressed in Escherichia coli BL21(RIL)-DE3 cells using [12C]-acetyl-CoA/[14C]-acetyl-CoA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50456444(CHEMBL3734823)
Affinity DataIC50:  1.60E+3nMAssay Description:Noncompetitive inhibition of P300 (1287 to 1652 residues) VMA intein chitin binding domain (unknown origin) expressed in Escherichia coli BL21(RIL)-D...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50456444(CHEMBL3734823)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of P300 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50456444(CHEMBL3734823)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of p300 (unknown origin) using H3 peptide and acetyl-coA as substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed