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Found 2 Enz. Inhib. hit(s) with Target = 'Histone deacetylase 1' and Ligand = 'BDBM119703'
TargetHistone deacetylase 1(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM119703(US8685992, 27)
Affinity DataIC50:  70nMAssay Description:Inhibition of C-terminal GST-tagged full length human HDAC1 expressed in baculovirus expression system in Sf9 cells using AMC-labeled RHKKAc as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM119703(US8685992, 27)
Affinity DataIC50:  71nMT: 2°CAssay Description:The reactions were carried out in a 96-well microplate for fluorometry in a 50 μl reaction volume. After the deacetylation reaction, Fluor-de-Ly...More data for this Ligand-Target Pair
In DepthDetails US Patent