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Found 3 Enz. Inhib. hit(s) with Target = 'Histone deacetylase 1' and Ligand = 'BDBM163628'
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM163628(SR-3212 | US10807944, Compound RLS2-137 | US117319...)
Affinity DataIC50:  1.70E+3nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM163628(SR-3212 | US10807944, Compound RLS2-137 | US117319...)
Affinity DataIC50:  1.70E+3nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central C(O) NH NH unit flanked by a phenyl group and a short aliphatic c...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Florida Research Foundation

US Patent
LigandPNGBDBM163628(SR-3212 | US10807944, Compound RLS2-137 | US117319...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of HDAC1 (unknown origin) using acetylated 7-amino-4-methylcoumarin (AMC) as peptide substrate measured after 20 mins by fluorescence base...More data for this Ligand-Target Pair
In DepthDetails PubMed