Found 67 Enz. Inhib. hit(s) with Target = 'Histone deacetylase 1' and Ligand = 'BDBM19410' 
Affinity DataKi: 7nMAssay Description:Inhibition of full length C-terminal His-tagged HDAC1 (unknown origin) assessed as rate constant (k-2) of EI complex using (Ac-Leu-Gly-Lys(Ac)-AMC as...More data for this Ligand-Target Pair
Affinity DataKi: 590nMAssay Description:Inhibition of full length C-terminal His-tagged HDAC1 (unknown origin) assessed as equilibrium inhibition constant (Ki,1) using (Ac-Leu-Gly-Lys(Ac)-A...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant human HDAC1 using pan-HDAC substrate incubated for 3 hrs by fluorescence methodMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:The following non-trypsin coupled in-vitro HDAC enzymatic endpoint assay was used to assay the compounds of the invention. Below is a standardized pr...More data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Inhibition of recombinant human HDAC1 using Cbz-Lys(TFAc)-AMC as substrate by fluorometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Inhibition of recombinant HDAC1 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition and meas...More data for this Ligand-Target Pair
Affinity DataIC50: 93nMAssay Description:Inhibition of HDAC1 (unknown origin) by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 99nMAssay Description:Inhibition of recombinant human full length HDAC1 using Fluor-de-Lys as substrate after 60 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of HDAC1 (mean IC50)More data for this Ligand-Target Pair
Affinity DataIC50: 118nMAssay Description:Inhibition of recombinant full length human HDAC1 expressed in baculovirus infected Sf9 cells using FAM-RHKK-Ac as substrate incubated for 17 hrs by ...More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of HDAC1 by fluorogenic enzyme assayMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of human C-terminal FLAG-tagged HDAC1 in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
Affinity DataIC50: 120nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibition of recombinant HDAC1 (unknown origin) using of Fluor-de-Lys substrate incubated for 10 mins by fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Inhibition of HDAC1 (unknown origin) using fluorogenic substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by flu...More data for this Ligand-Target Pair
Affinity DataIC50: 163nMAssay Description:Inhibition of HDAC1 (unknown origin) using Boc-Lys (acetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition measured after 1 hr...More data for this Ligand-Target Pair
Affinity DataIC50: 163nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 178nMAssay Description:Inhibition of HDAC1 (unknown origin) by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Displacement of [3H]-acetylated histones from HDAC1 derived from human K562 cell nuclear extract incubated for 10 mins by liquid scintillation counti...More data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Inhibition of full length recombinant human HDAC1 (1 to 482 residues) expressed in Baculovirus system using Ac-Leu-Gly-Lys (Ac)-AMC as substrate pret...More data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Inhibition of human recombinant HDAC1 incubated for 60 mins by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Inhibition of human recombinant C-terminal His/FLAG-tagged HDAC1 using Boc-Lys-(epsilon-Ac)-AMC as fluorogenic substrate incubated for 90 mins by flu...More data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Inhibition of human recombinant HDAC1 (unknown origin) using MAZ1600 as substrate preincubated for 3 hrs followed by substrate addition by multilabel...More data for this Ligand-Target Pair
Affinity DataIC50: 243nMpH: 7.5Assay Description:Biochemical assays of HDAC activity were carried out by Nanosyn in a reaction volume of 10 ul in 384-well microplates. A standard enzymatic reaction ...More data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:HDACs assay was performed according to standard Protocols (Fluorgenic HDACs 1, 2, and 3 assay kit, BPS Bioscience™). All of the compounds, with Chida...More data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:HDACs assay was performed according to standard Protocols (Fluorgenic HDACs 1, 2, and 3 assay kit, BPS Bioscience™). All of the compounds, with Chida...More data for this Ligand-Target Pair
Affinity DataIC50: 271nMAssay Description:Inhibition of HDAC1 (unknown origin) using Ac-Leu-GlyLys(Ac)-AMC as substrate preincubated for 10 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
Affinity DataIC50: 273nMAssay Description:Inhibition of HDAC1 (unknown origin) preincubated for 5 mins followed by fluorogenic substrate addition measured after 30 mins by microplate reader a...More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of human HDAC1 in U937 cells by immunoprecipitation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of HDAC1 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 310nMAssay Description:Inhibition of human recombinant HDAC1 using p53 residues 379-382 (RHKKAc) as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 340nMAssay Description:Inhibition of purified human HDAC1 using Ac-Leu-Gly-(e-Ac)Lys-AMC by fluorometric HDAC assayMore data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibition of human recombinant His-tagged HDAC1 (482 residues) expressed in baculovirus infected insect cells using FLUOR DE LYS SIRT1 as substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibition of human recombinant HDAC1 using Fluor de Lys-Green as substrate preincubated for 5 mins followed by substrate addition and measured after...More data for this Ligand-Target Pair
Affinity DataIC50: 390nMAssay Description:Inhibition of recombinant HDAC1 (unknown origin) incubated for 10 mins using Boc-Lys(acetyl)-AMC fluorogenic substrate by homogeneous fluorescence re...More data for this Ligand-Target Pair
Affinity DataIC50: 390nMAssay Description:Inhibition of recombinant HDAC1 (unknown origin) using fluorogenic substrate Boc-Lys (acetyl)-AMC after 20 mins by homogeneous fluorescence release a...More data for this Ligand-Target Pair
Affinity DataIC50: 410nMAssay Description:Inhibition of HDAC1 (unknown origin) using deacetylase fluorogenic substrate pretreated for 5 mins followed by substrate addition after 30 mins by fl...More data for this Ligand-Target Pair
Affinity DataIC50: 485nMAssay Description:Inhibition of purified recombinant HDAC1More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of HDAC1 using Fluor de Lys as substrate by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 510nMAssay Description:Inhibition of HADC1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 519nMAssay Description:Inhibition of recombinant human full length C-terminal His/FLAG-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells using ZMAL as substra...More data for this Ligand-Target Pair
Affinity DataIC50: 540nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
