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Found 2 Enz. Inhib. hit(s) with Target = 'Histone deacetylase 1' and Ligand = 'BDBM465374'
TargetHistone deacetylase 1(Homo sapiens (Human))
Alkermes

US Patent
LigandPNGBDBM465374(US10793567, Compound 8 | US11225479, Compound 8)
Affinity DataIC50:  300nMAssay Description:The following describes an assay protocol for measuring the deacetylation of a peptide substrate by the enzymes HDAC2 or HDAC1. Enzyme, substrate, an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Alkermes

US Patent
LigandPNGBDBM465374(US10793567, Compound 8 | US11225479, Compound 8)
Affinity DataIC50:  1.25E+3nMAssay Description:The following describes an assay protocol for measuring the deacetylation of a peptide substrate by the enzymes HDAC2 or HDAC1. Enzyme, substrate, an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent