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Found 3 Enz. Inhib. hit(s) with Target = 'Histone deacetylase 6' and Ligand = 'BDBM337666'
TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM337666(US10227295, Compound JB7-20 | US9751832, Compound ...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of recombinant human full length HDAC6 expressed in baculovirus infected Sf9 insect cells using p53 (379 to 382 residues) derived RHKKAc a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM337666(US10227295, Compound JB7-20 | US9751832, Compound ...)
Affinity DataIC50:  6.12nMAssay Description:HDAC inhibition assays were performed by Reaction Biology Corp. (Malvern, Pa.) using isolated human, recombinant full-length HDAC1 and -6 from a bacu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM337666(US10227295, Compound JB7-20 | US9751832, Compound ...)
Affinity DataIC50:  6.12nMAssay Description:HDAC inhibition assays were performed by Reaction Biology Corp. (Malvern, Pa.) using isolated human, recombinant full-length HDAC1 and -6 from a bacu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent