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Found 2 Enz. Inhib. hit(s) with Target = 'Histone deacetylase 8' and Ligand = 'BDBM119703'
TargetHistone deacetylase 8(Homo sapiens (Human))
Universidad Del PaíS Vasco

US Patent
LigandPNGBDBM119703(US8685992, 27)
Affinity DataIC50:  148nMT: 2°CAssay Description:The reactions were carried out in a 96-well microplate for fluorometry in a 50 μl reaction volume. After the deacetylation reaction, Fluor-de-Ly...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Universidad Del PaíS Vasco

US Patent
LigandPNGBDBM119703(US8685992, 27)
Affinity DataIC50:  150nMAssay Description:Inhibition of full length human HDAC8 expressed in an E. coli expression system using AMC-labeled RHKAcKAc as substrate after 2 hrs by fluorescence a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed