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Found 4 Enz. Inhib. hit(s) with Target = 'Histone-lysine N-methyltransferase EHMT1' and Ligand = 'BDBM50442103'
TargetHistone-lysine N-methyltransferase EHMT1(Homo sapiens (Human))TBA
LigandPNGBDBM50442103(CHEMBL2441082)
Affinity DataIC50: <2.5nMAssay Description:Inhibition of GLP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Homo sapiens (Human))TBA
LigandPNGBDBM50442103(CHEMBL2441082)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of GLP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Homo sapiens (Human))TBA
LigandPNGBDBM50442103(CHEMBL2441082)
Affinity DataIC50:  180nMAssay Description:Inhibition of human GLP (982 to 1266 residues) using H3 peptide as substrate measured upto 45 mins in presence of SAM cofactorMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Homo sapiens (Human))TBA
LigandPNGBDBM50442103(CHEMBL2441082)
Affinity DataKd:  62nMAssay Description:Binding affinity to human GLP (982 to 1266 residues) assessed as dissociation constant by isothermal titration calorimetry methodMore data for this Ligand-Target Pair
In DepthDetails PubMed