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Report error Found 3 Enz. Inhib. hit(s) with Target = 'Indoleamine 2,3-dioxygenase 1' and Ligand = 'BDBM317215'
TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandChemical structure of BindingDB Monomer ID 317215BDBM317215(US9617272, Compound 70 | US9981973, Compound 70)
Affinity DataIC50: 100nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandChemical structure of BindingDB Monomer ID 317215BDBM317215(US9617272, Compound 70 | US9981973, Compound 70)
Affinity DataIC50: 1.00E+3nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandChemical structure of BindingDB Monomer ID 317215BDBM317215(US9617272, Compound 70 | US9981973, Compound 70)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of C-terminal 6His-tagged human IDO using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed