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Found
1
Enz. Inhib. hit(s) with Target = 'Indoleamine 2,3-dioxygenase 1' and Ligand = 'BDBM503514'
Target
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Ligand
BDBM503514
(4-[(azetidin-3-yl)oxy]-N-[(7S)-4- fluorobicyclo[4...)
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Affinity Data
IC50: 224nM
Assay Description:
HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...
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Ligand Info
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