Found 3 Enz. Inhib. hit(s) with Target = 'Indoleamine 2,3-dioxygenase 1' and Ligand = 'BDBM50509626'
Affinity DataIC50: 21nMAssay Description:Inhibition of IDO1 in interferon-gamma-induced human SKOV3 cells assessed as N-formylkynurenine formation using L-tryptophan as substrate measured af...More data for this Ligand-Target Pair
Affinity DataIC50: 93nMAssay Description:Inhibition of human N-terminal GST-tagged IDO1 expressed in Escherichia coli Rosetta(DE3) pLysS using L-tryptophan as substrate measured after 1 hr b...More data for this Ligand-Target Pair
Affinity DataIC50: 320nMAssay Description:Inhibition IDO1 in LPS/IFN-gamma stimulated human whole blood assessed as reduction in tryptophan/kynurenine level preincubated for 15 mins followed ...More data for this Ligand-Target Pair