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Found 2 Enz. Inhib. hit(s) with Target = 'Indoleamine 2,3-dioxygenase 1' and Ligand = 'BDBM50509628'
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Phenex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50509628(CHEMBL4434929)
Affinity DataIC50:  12nMAssay Description:Inhibition of IDO1 in interferon-gamma-induced human SKOV3 cells assessed as N-formylkynurenine formation using L-tryptophan as substrate measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Phenex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50509628(CHEMBL4434929)
Affinity DataIC50:  110nMAssay Description:Inhibition of human N-terminal GST-tagged IDO1 expressed in Escherichia coli Rosetta(DE3) pLysS using L-tryptophan as substrate measured after 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed