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Found 3 Enz. Inhib. hit(s) with Target = 'Indoleamine 2,3-dioxygenase 2' and Ligand = 'BDBM50442987'
TargetIndoleamine 2,3-dioxygenase 2(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50442987(8-Bromotryptanthrin | CHEMBL72165)
Affinity DataKi:  5.60E+3nMAssay Description:Uncompetitive inhibition of recombinant human C-terminal His6-tagged IDO2 (14-420 residues) expressed in Escherichia coli BL21(DE3) in presence of va...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 2(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50442987(8-Bromotryptanthrin | CHEMBL72165)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of recombinant human IDO2 expressed in human U87MG cells assessed as reduction in kynurenine formation using L-tryptophan as substrate aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 2(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50442987(8-Bromotryptanthrin | CHEMBL72165)
Affinity DataIC50:  8.30E+3nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged IDO2 (14-420 residues) expressed in Escherichia coli BL21(DE3) assessed as reduction in L-kynu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed