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Found 2 Enz. Inhib. hit(s) with Target = 'Inhibitor of nuclear factor kappa-B kinase subunit beta' and Ligand = 'BDBM569251'
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM569251(US11427563, Compound 118 | US11427563, Compound 12...)
Affinity DataIC50:  0.600nMAssay Description:All compounds were initially prepared as 10 mM stocks in anhydrous dimethylsulfoxide (DMSO). A 20 μl aliquot of the 10 mM solutions was transfer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM569251(US11427563, Compound 118 | US11427563, Compound 12...)
Affinity DataIC50:  8nMAssay Description:All compounds were initially prepared as 10 mM stocks in anhydrous dimethylsulfoxide (DMSO). A 20 μl aliquot of the 10 mM solutions was transfer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent