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Found 2 Enz. Inhib. hit(s) with Target = 'Integrin alpha-V/beta-3' and Ligand = 'BDBM50217434'
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50217434(2S,4R,20S-4-{[2-carboxy-2-(2,4,6-trimethyl-benzoyl...)
Affinity DataIC50:  1.20E+3nMAssay Description:Antagonist activity at integrin alphavbeta3 in human A375M cells assessed as inhibition of cell adhesion to fibrinogen in presence of Mg2+More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50217434(2S,4R,20S-4-{[2-carboxy-2-(2,4,6-trimethyl-benzoyl...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of integrin alphaVbeta3 receptor by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed