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Found 5 Enz. Inhib. hit(s) with Target = 'Integrin alpha-V/beta-6' and Ligand = 'BDBM50110227'
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50110227(3-{2-[4-(4-Methyl-pyridin-2-ylamino)-butyrylamino]...)
Affinity DataIC50:  0.0400nMAssay Description:Inhibition of fibronectin binding to recombinant human alphaV-beta6 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50110227(3-{2-[4-(4-Methyl-pyridin-2-ylamino)-butyrylamino]...)
Affinity DataIC50:  0.0400nMAssay Description:Inhibition of integrin alphavbeta6 (unknown origin) by Merck binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50110227(3-{2-[4-(4-Methyl-pyridin-2-ylamino)-butyrylamino]...)
Affinity DataIC50:  4nMAssay Description:Inhibition of latency-associated peptide binding to Integrin alphaVbeta6 receptor (unknown origin) by competitive ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50110227(3-{2-[4-(4-Methyl-pyridin-2-ylamino)-butyrylamino]...)
Affinity DataIC50:  200nMAssay Description:Inhibition of integrin alphavbeta6 (unknown origin)-mediated K562 cell adhesion to LAPb1 coated surface by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50110227(3-{2-[4-(4-Methyl-pyridin-2-ylamino)-butyrylamino]...)
Affinity DataIC50:  200nMAssay Description:Inhibition of integrin alpha-v/beta-6 mediated UCLAP-3 cell adhesion to fibronectinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed