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Found 3 Enz. Inhib. hit(s) with Target = 'Kappa-type opioid receptor' and Ligand = 'BDBM156541'
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

US Patent
LigandPNGBDBM156541(US10118915, Compound 324 | US9682966, 324)
Affinity DataIC50:  1.30nMT: 2°CAssay Description:The cell line for the OPRK1 antagonist assay stably expresses the following elements. The carboxy terminus of the OPRK1 receptor has a 7 amino acid l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

US Patent
LigandPNGBDBM156541(US10118915, Compound 324 | US9682966, 324)
Affinity DataIC50:  1.30nMAssay Description:Antagonist activity at GAL4-VP16-fused KOR (unknown origin) expressed in human U2OS cells co-expressing Tango-OPRK1-BLA assessed as inhibition of U-5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

US Patent
LigandPNGBDBM156541(US10118915, Compound 324 | US9682966, 324)
Affinity DataIC50:  1.30nMAssay Description:Well-known assay for kappa opioid receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent