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Found 2 Enz. Inhib. hit(s) with Target = 'Kelch-like ECH-associated protein 1' and Ligand = 'BDBM50593815'
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
The State University Of New Jersey

Curated by ChEMBL
LigandPNGBDBM50593815(CHEMBL5184245)
Affinity DataIC50:  14nMAssay Description:Inhibition of His-tagged Keap1 kelch domain/Nrf2 (unknown origin) protein-protein interaction using FITC-LDEETGEFL-NH2 peptide as substrate preincuba...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
The State University Of New Jersey

Curated by ChEMBL
LigandPNGBDBM50593815(CHEMBL5184245)
Affinity DataIC50:  65nMAssay Description:Inhibition of recombinant human Keap1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3)pLysS cells/Nrf2 (unknown origin) pr...More data for this Ligand-Target Pair
In DepthDetails PubMed