Compile Data Set for Download or QSAR
maximum 50k data
Found 8 Enz. Inhib. hit(s) with Target = 'Kinesin-like protein KIF11' and Ligand = 'BDBM50431886'
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50431886(CHEMBL1413473)
Affinity DataIC50:  740nMAssay Description:Inhibition of basal ATPase activity of N-terminal His6-tagged human Eg5 motor domain (1 to 368 residues) expressed in Escherichia coli BL21 (DE3) by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50431886(CHEMBL1413473)
Affinity DataIC50:  740nMAssay Description:Inhibition of N-terminal His6-tagged microtubule-stimulated ATPase activity of human Eg5 motor domain (1 to 368 residues) expressed in Escherichia co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50431886(CHEMBL1413473)
Affinity DataIC50:  800nMAssay Description:Inhibition of MT-stimulated EG5 ATPase activity (unknown origin) by pyruvate kinase/lactate dehydrogenase enzyme coupled photometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50431886(CHEMBL1413473)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of microtubule-stimulated recombinant human Eg5 ATPase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50431886(CHEMBL1413473)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of Eg5 in human HCT116 cells assessed as inhibition of microtubule-induced ATPase activity after 18 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50431886(CHEMBL1413473)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of Eg5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50431886(CHEMBL1413473)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition EG5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50431886(CHEMBL1413473)
Affinity DataKd:  665nMAssay Description:Binding affinity to N-terminal His6-tagged human Eg5 motor domain (1 to 368 residues) expressed in Escherichia coli BL21 (DE3) by isothermal titratio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed