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Found 5 Enz. Inhib. hit(s) with Target = 'L-lactate dehydrogenase A chain' and Ligand = 'BDBM50144744'
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Hubei University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50144744(Sodium Oxamate)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human LDHA expressed in Escherichia coli BL21 (DE3) using sodium pyruvate as substrate by Lineweaver-Burk plot methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Hubei University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50144744(Sodium Oxamate)
Affinity DataKi:  1.36E+5nMAssay Description:Inhibition of human LDHA using sodium pyruvate as substrateMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Hubei University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50144744(Sodium Oxamate)
Affinity DataIC50:  1.65E+4nMAssay Description:Inhibition of LDHA in human Med1 cells using pyruvate as substrate incubated 10 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Hubei University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50144744(Sodium Oxamate)
Affinity DataIC50:  1.31E+5nMAssay Description:Competitive inhibition of human LDH5 in presence of NADHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Hubei University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50144744(Sodium Oxamate)
Affinity DataEC50:  1.20E+6nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged LDHA (1 to 332 residues) expressed in Escherichia coli using sodium pyruvate as sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed