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Found 2 Enz. Inhib. hit(s) with Target = 'Leucine--tRNA ligase, cytoplasmic' and Ligand = 'BDBM50241780'
TargetLeucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Anacor Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50241780(CHEMBL4105269)
Affinity DataIC50:  9.66E+4nMAssay Description:Inhibition of human N-terminal 6His-tagged cytoplasmic LeuRS expressed in Escherichia coli BL21(DE3) assessed as L-[14C]leucine incorporation in to E...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Anacor Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50241780(CHEMBL4105269)
Affinity DataEC50:  8.28E+4nMAssay Description:Inhibition of cytoplasmic LeuRS in human HepG2 cells assessed as reduction in protein synthesis preincubated for 48 hrs followed by L-[14C]leucine ad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed