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Found 3 Enz. Inhib. hit(s) with Target = 'Liver carboxylesterase 1' and Ligand = 'BDBM50233190'
TargetLiver carboxylesterase 1(Homo sapiens (Human))
South China University Of Technology

Curated by ChEMBL
LigandPNGBDBM50233190(CHEMBL4104953)
Affinity DataKi:  16nMAssay Description:Inhibition of human liver carboxylesterase 1 using o-nitrophenyl acetate as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Homo sapiens (Human))
South China University Of Technology

Curated by ChEMBL
LigandPNGBDBM50233190(CHEMBL4104953)
Affinity DataKi:  38nMAssay Description:Inhibition of human liver CES1 expressed in baculovirus infected sf9 cells using oseltamivir as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Homo sapiens (Human))
South China University Of Technology

Curated by ChEMBL
LigandPNGBDBM50233190(CHEMBL4104953)
Affinity DataKi:  163nMAssay Description:Induction of ERalpha degradation in tamoxifen-sensitive human MCF7:WS8 cells after 24 hrs by CellTag 700 staining based In-cell western assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed