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Found 4 Enz. Inhib. hit(s) with Target = 'Lysine-specific demethylase 2A' and Ligand = 'BDBM50158853'
TargetLysine-specific demethylase 2A(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50158853(CHEMBL3786188)
Affinity DataKi:  1.50E+3nMAssay Description:Competitive inhibition of recombinant His6-tagged KDM2A (1 to 517 residues) (unknown origin) expressed in Escherichia coli BL21 cells using methylsta...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 2A(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50158853(CHEMBL3786188)
Affinity DataIC50:  280nMAssay Description:Inhibition of KDM2A in human MIA PaCa-2 cells assessed as induction of H3K36me2 measured by immunofluorescence assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetLysine-specific demethylase 2A(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50158853(CHEMBL3786188)
Affinity DataEC50:  900nMAssay Description:Inhibition of KDM2A in human MIAPaCa2 cells assessed as increase in H3K9me3 level after 48 hrs by Hoechst 33258 staining based immunofluorescence ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 2A(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50158853(CHEMBL3786188)
Affinity DataEC50:  930nMAssay Description:Inhibition of KDM2A in human MIAPaCa2 cells assessed as increase in H3K36me2 level after 48 hrs by Hoechst 33258 staining based immunofluorescence as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed