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Found 6 Enz. Inhib. hit(s) with Target = 'Lysine-specific demethylase 4C' and Ligand = 'BDBM293660'
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Celgene Quanticel Research

Curated by ChEMBL
LigandPNGBDBM293660(3-({[(1S)-6-[methyl(phenyl)amino]-1,2,3,4-tetrahyd...)
Affinity DataIC50:  9nMAssay Description:Inhibition of KDM4C (unknown origin) using biotinylated H3K9me3 peptide and alpha-ketoglutarate as substrate pretreated for 1 hr followed by substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Celgene Quanticel Research

Curated by ChEMBL
LigandPNGBDBM293660(3-({[(1S)-6-[methyl(phenyl)amino]-1,2,3,4-tetrahyd...)
Affinity DataIC50:  35nMAssay Description:Inhibition of KDM4C (unknown origin) using biotinylated H3K9me3 peptide and alpha-ketoglutarate as substrate pretreated for 1 hr followed by substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Celgene Quanticel Research

Curated by ChEMBL
LigandPNGBDBM293660(3-({[(1S)-6-[methyl(phenyl)amino]-1,2,3,4-tetrahyd...)
Affinity DataIC50:  35nMAssay Description:Inhibition of KDM4C (unknown origin) using H3K9me3 as substrate and measured by LANCE TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Celgene Quanticel Research

Curated by ChEMBL
LigandPNGBDBM293660(3-({[(1S)-6-[methyl(phenyl)amino]-1,2,3,4-tetrahyd...)
Affinity DataIC50:  550nMT: 2°CAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Celgene Quanticel Research

Curated by ChEMBL
LigandPNGBDBM293660(3-({[(1S)-6-[methyl(phenyl)amino]-1,2,3,4-tetrahyd...)
Affinity DataEC50:  1.30nMAssay Description:Inhibition of KDM4C in human KYSE-150 cells overexpressing KDM4C assessed as increase in H3K36me3 measured by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Celgene Quanticel Research

Curated by ChEMBL
LigandPNGBDBM293660(3-({[(1S)-6-[methyl(phenyl)amino]-1,2,3,4-tetrahyd...)
Affinity DataEC50:  1.30nMAssay Description:Inhibition of full-length KDM4C (unknown origin) expressed in human KYSE-150 cells assessed as increase in H3K36me3 level after 24 hrs by Western blo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed