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Found 3 Enz. Inhib. hit(s) with Target = 'Lysine-specific demethylase 4E' and Ligand = 'BDBM50361146'
TargetLysine-specific demethylase 4E(Homo sapiens (Human))
Max Delbr�Ck Center For Molecular Medicine In The Helmholtz Gemeinschaft (Mdc)

Curated by ChEMBL
LigandPNGBDBM50361146(CHEMBL1933775)
Affinity DataIC50:  900nMAssay Description:Inhibition of N-terminal His6-tagged KDM4E (1 to 337 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-R3 preincubated for 10 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 4E(Homo sapiens (Human))
Max Delbr�Ck Center For Molecular Medicine In The Helmholtz Gemeinschaft (Mdc)

Curated by ChEMBL
LigandPNGBDBM50361146(CHEMBL1933775)
Affinity DataIC50:  900nMAssay Description:Inhibition of N-terminal His6-tagged human KDM4E (1 to 337 residues) catalytic domain measured formaldehyde dehydrogenase (FDH)-coupled fluorescence ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetLysine-specific demethylase 4E(Homo sapiens (Human))
Max Delbr�Ck Center For Molecular Medicine In The Helmholtz Gemeinschaft (Mdc)

Curated by ChEMBL
LigandPNGBDBM50361146(CHEMBL1933775)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of N-terminal His6-tagged KDM4E (1 to 337 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-R3 preincubated for 10 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed