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Found 5 Enz. Inhib. hit(s) with Target = 'Lysine-specific demethylase 5C' and Ligand = 'BDBM195608'
TargetLysine-specific demethylase 5C(Homo sapiens (Human))
Genentech

LigandPNGBDBM195608(CPI-455)
Affinity DataIC50:  14nMpH: 7.0Assay Description:Time-resolved fluorescence resonance energy transfer (TR-FRET) assays were carried out using full-length KDM5 enzymes in 384-well black ProxiPlates (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5C(Homo sapiens (Human))
Genentech

LigandPNGBDBM195608(CPI-455)
Affinity DataIC50:  14nMAssay Description:Inhibition of KDM5C (unknown origin) using ART(Kme3)QTARKSTGGKAPRKQLA-NovaTagPEG-biotin/2-OG as substrate/co-factor by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5C(Homo sapiens (Human))
Genentech

LigandPNGBDBM195608(CPI-455)
Affinity DataIC50:  14nMAssay Description:Inhibition of KDM5C (unknown origin ) by HTMS assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetLysine-specific demethylase 5C(Homo sapiens (Human))
Genentech

LigandPNGBDBM195608(CPI-455)
Affinity DataIC50:  14nMAssay Description:Inhibition of KDM5C (unknown origin) using ART(Kme3)QTARKSTGGKAPRKQLA-NovaTagPEG-biotin/2-OG as substrate/co-factor by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5C(Homo sapiens (Human))
Genentech

LigandPNGBDBM195608(CPI-455)
Affinity DataIC50:  3.01E+3nMAssay Description:Inhibition of full-length human N-terminal FLAG/His-tagged KDM5C (2 to 1560 residues) expressed in baculovirus infected Sf9 insect cells using H3(1-2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed