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Found 3 Enz. Inhib. hit(s) with Target = 'Major prion protein' and Ligand = 'BDBM50333113'
TargetMajor prion protein(Mus musculus)
Gifu University

Curated by ChEMBL
LigandPNGBDBM50333113(8-methyl-7-(2-(piperidin-1-yl)ethylthio)-2,3-dihyd...)
Affinity DataKd:  5.08E+4nMAssay Description:Binding affinity to mouse recombinant PrP (121-231) after 10 mins by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMajor prion protein(Mesocricetus auratus)
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50333113(8-methyl-7-(2-(piperidin-1-yl)ethylthio)-2,3-dihyd...)
Affinity DataKd:  5.08E+4nMAssay Description:Binding affinity to Syrian hamster PrPCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMajor prion protein(Mesocricetus auratus)
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50333113(8-methyl-7-(2-(piperidin-1-yl)ethylthio)-2,3-dihyd...)
Affinity DataEC50:  7.32E+3nMAssay Description:Binding affinity to Syrian hamster PrPC assessed as inhibition of PrPC protein conversion to PrPSc by Western blotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed