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Found 9 Enz. Inhib. hit(s) with Target = 'Matrix metalloproteinase-9' and Ligand = 'BDBM50264809'
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50264809(2-((4-phenoxyphenylsulfonyl)methyl)thiirane | CHEM...)
Affinity DataKi:  400nMAssay Description:Inhibition of recombinant human MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50264809(2-((4-phenoxyphenylsulfonyl)methyl)thiirane | CHEM...)
Affinity DataKi:  400nMAssay Description:Inhibition of MMP-9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50264809(2-((4-phenoxyphenylsulfonyl)methyl)thiirane | CHEM...)
Affinity DataKi:  600nMAssay Description:Competitive inhibition of human MMP9 using fluorogenic substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50264809(2-((4-phenoxyphenylsulfonyl)methyl)thiirane | CHEM...)
Affinity DataKi:  600nMAssay Description:Competitive inhibition of human MMP-9 assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50264809(2-((4-phenoxyphenylsulfonyl)methyl)thiirane | CHEM...)
Affinity DataKi:  600nMAssay Description:Inhibition of recombinant human MMP9 expressed in human HeLaS3 cells using MOCAcPLGLA2pr(Dnp)-AR-NH2 as substrate incubated for 15 to 30 mins by fluo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50264809(2-((4-phenoxyphenylsulfonyl)methyl)thiirane | CHEM...)
Affinity DataKi:  600nMAssay Description:Inhibition of human recombinant MMP9 catalytic domain by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50264809(2-((4-phenoxyphenylsulfonyl)methyl)thiirane | CHEM...)
Affinity DataKi:  600nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50264809(2-((4-phenoxyphenylsulfonyl)methyl)thiirane | CHEM...)
Affinity DataKi:  2.10E+3nMAssay Description:Human recombinant active MMP-2 and MMP-7, and the catalytic domains of MMP-3 and MMP-14/MT1-MMP were purchased from EMD Chemicals, Inc. (San Diego, C...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50264809(2-((4-phenoxyphenylsulfonyl)methyl)thiirane | CHEM...)
Affinity DataIC50:  400nMAssay Description:In vitro inhibitory activity against beta-1 adrenergic receptor determined as pA2 in guinea pig atriaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed